| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Dystrobrevin alpha |
| Specificity: |
This antibody reacts specifically with Dystrobrevin alpha |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Dystrobrevin alpha/DRP3 |
| Gene ID: |
1837 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Dystrobrevin alpha may be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors, It is a component of the dystrophin associated protein complex (DPC), Mutations in Dystrobrevin alpha are associated with left ventricular noncompaction with congenital heart defects, The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy, including dystroglycans, sarcoglycans, syntrophins and alpha and beta dystrobrevin, which consists of dystrophin and several integral and peripheral membrane proteins, Dystrobrevin alpha belongs to the dystrobrevin subfamily of the dystrophin family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D18S892E DTN DTN-1 DTN-2 DTN-3 DRP3 |
| Also known as: |
Dystrobrevin alpha Polyclonal Antibody |
| Other name: |
Anti-Dystrobrevin alpha Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Dystrobrevin alpha |
| Short name: |
Anti-Dystrobrevin alpha (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Dystrobrevin a (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3057 |
| Gene: |
DTNA |
More about : DTNA |
| Long gene name: |
dystrobrevin alpha |
| Synonyms gene name: |
alpha , dystrobrevin |
| Synonyms name: |
dystrophin-related protein 3 |
| Locus: |
18q12, 1 |
| Discovery year: |
1998-02-11 |
| GenBank acession: |
U84540 |
| Entrez gene record: |
1837 |
| Pubmed identfication: |
8081380 15834686 |
| RefSeq identity: |
NM_001390 |
| Classification: |
Zinc fingers ZZ-type |
| Havana BLAST/BLAT: |
OTTHUMG00000132309 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_756 |