| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
p70 S6 Kinase Beta 2 Tyr389 |
| Specificity: |
This antibody reacts specifically with p70 S6 Kinase Beta 2 (Tyr389) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr389 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human p70 S6 Kinase Beta 2 around the phosphorylation site of Tyr389 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
By this basic mechanism, The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains, With more than 500 gene products, and differentiation, apoptosis, cell cycle progression, cytoskeletal rearrangement and cell movement, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, the protein kinase family is one of the largest families of proteins in eukaryotes, transcription, Protein kinases are enzymes that transfer a phosphate group from a phosphate donor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
70 kDa ribosomal protein S6 kinase 2, RPS6KB2, Ribosomal protein S6 kinase 70kDa, Ribosomal protein S6 kinase beta 2, Ribosomal protein S6 kinase beta-2, S6 kinase related kinase, S6 kinase-related kinase, S6K beta, S6K beta 2, S6K phospho Y389, S6K-beta, S6K2, SRK, STK14B, Serine/threonine protein kinase 14 beta, Serine/threonine-protein kinase 14 beta, p-S6KTyr389, p70 S6 Kinase Beta 2 phospho Tyr389, p70 S6 kinase beta, p70 S6KB, p70 S6Kbeta, p70 beta, p70 ribosomal S6 kinase beta, p70-S6KB, p70-beta, p70S6K beta, p70S6Kb, polypeptide 2, RPS6KB2phospho Y389 |
| Also known as: |
p70 S6 Kinase Beta 2 (Tyr389) Antibody |
| Other name: |
Anti-p70 S6 Kinase Beta 2 (Tyr389) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
p70 S6 Kinase Beta 2 (Tyr389) |
| Short name: |
Anti-p70 S6 Kinase Beta 2 (Tyr389) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-p70 S6 phosphorylation catalyst b 2 (Tyr389) |