| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SGK1 Ser78 |
| Specificity: |
This antibody reacts specifically with SGK1 (Ser78) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser78 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Ser78 |
| Gene ID: |
6446 |
| Swiss Prot: |
O00141 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy, Jan 2009], Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene, This kinase activates certain potassium, [provided by RefSeq, and chloride channels, and renal sodium excretion, neuronal excitability, sodium, suggesting an involvement in the regulation of processes such as cell survival, This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
SGK1 (Ser78) Polyclonal Antibody |
| Other name: |
Anti-SGK1 (Ser78) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SGK1 (Ser78) |
| Short name: |
Anti-SGK1 (Ser78) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-serum/glucocorticoid regulated kinase 1 (Ser78) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
SGK, SGK1 and IDBG-633483 and ENSBTAG00000004269 and 515854, SGK1 and IDBG-96775 and ENSG00000118515 and 6446, Sgk1 and IDBG-137283 and ENSMUSG00000019970 and 20393, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005246 and calcium channel regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006814 and sodium ion transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0006950 and response to stress and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007616 and long-term memory and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004712 : protein serine/threonine/tyrosine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005246 : calcium channel regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004712 : protein serine/threonine/tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005246 : calcium channel regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0015459 : potassium channel regulator activity, this GO :0016772 : transferase activity, this GO :0017080 : sodium channel regulator activity, this GO :0017081 : chloride channel regulator activity, this GO :0035091 : phosphatidylinositol binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017080 : sodium channel regulator activity and also this GO :0017081 : chloride channel regulator activity and also this GO :0035091 : phosphatidylinositol binding, transferring phosphorus-containing groups and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0017081 and chloride channel regulator activity and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0032411 and positive regulation of transporter activity and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042127 and regulation of cell proliferation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060453 and regulation of gastric acid secretion and biological process this GO :0070294 and renal sodium ion absorption and biological process, serum/glucocorticoid regulated kinase 1 |
| Identity: |
10810 |
| Gene: |
SGK1 |
More about : SGK1 |
| Long gene name: |
serum/glucocorticoid regulated kinase 1 |
| Synonyms gene: |
SGK |
| Synonyms gene name: |
serum/glucocorticoid regulated kinase |
| Locus: |
6q23, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
AJ000512 |
| Entrez gene record: |
6446 |
| Pubmed identfication: |
9114008 9722955 |
| Havana BLAST/BLAT: |
OTTHUMG00000015613 |