| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
p90RSK Ser380 |
| Specificity: |
This antibody reacts specifically with p90RSK (Ser380) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser380 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human p90RSK around the phosphorylation site of Ser380 |
| Gene ID: |
6196 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB, Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation, Rsk2 and Rsk3, These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2, which includes Rsk1, Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
90 kDa ribosomal protein S6 kinase 1, 90kD, EC 2, HU 1, HU1, MAP kinase activated protein kinase 1a, MAPKAP kinase 1A, MAPKAPK1A, MGC79981, Mitogen-activated protein kinase-activated protein kinase 1A, OTTHUMP00000004113, RPS6K1 alpha, RSK, RSK 1, RSK 1 p90, RSK1, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase 90kD 1, Ribosomal protein S6 kinase 90kD polypeptide 1, Ribosomal protein S6 kinase 90kDa polypeptide 1, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase polypeptide 1, Rps6ka1, S6K alpha 1, dJ590P13, dJ590P13, p90S6K, p90rsk, polypeptide 1, pp90RSK1, rps6ka, 1, 1, 1 ribosomal protein S6 kinase, 7, 11, p90 RSK1 |
| Also known as: |
p90RSK (Ser380) Polyclonal Antibody |
| Other name: |
Anti-p90RSK (Ser380) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
p90RSK (Ser380) |
| Short name: |
Anti-p90RSK (Ser380) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-p90RSK (Ser380) (polyclonal) |
| Alternative technique: |
polyclonals |