| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PDGF Receptor beta Tyr751 |
| Specificity: |
This antibody reacts specifically with PDGF Receptor beta (Tyr751) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr751 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human PDGF Receptor beta around the phosphorylation site of Tyr751 [VD(p-Y)VP] |
| Gene ID: |
5159 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A translocation between chromosomes 5 and 12, ETV6, The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, These growth factors are mitogens for cells of mesenchymal origin, This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, [provided by RefSeq], all three genes may be implicated in the 5-q syndrome, composed of both platelet-derived growth factor receptor alpha and beta polypeptides, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia, that fuses this gene to that of the translocation, This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Beta platelet derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD 140B, CD140 antigen-like family member B, CD140B, CD140B, CD140b antigen, JTK12, OTTHUMP00000160528, PDGF R beta, PDGF Receptor beta phospho Tyr751, PDGF Receptor beta phospho Y751, PDGF-R-beta, PDGFR, PDGFR 1, PDGFR beta, PDGFR1, PDGFRB, PDGFRBTyr751, PGFRB_HUMAN, Platelet derived growth factor receptor 1, Platelet derived growth factor receptor beta, Platelet derived growth factor receptor beta, polypeptide, PDGFRBphospho Y751 |
| Also known as: |
PDGF Receptor beta (Tyr751) Antibody |
| Other name: |
Anti-PDGF Receptor beta (Tyr751) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PDGF Receptor beta (Tyr751) |
| Short name: |
Anti-PDGF Receptor beta (Tyr751) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PDGF Receptor b (Tyr751) |