| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
STK39 |
| Specificity: |
This antibody reacts specifically with STK39 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PASK/STK39 |
| Gene ID: |
27347 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases, DCHT or PASK, Expressed predominately in pancreas, SPAK, SPAK functions as a Ser/Thr protein kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in mediating stress-activated signals, The gene encoding SPAK maps to human chromosome 2, also known as STK39 (serine threonine kinase 39), brain, heart, homeostasis and apoptosis, including cell division, is a 547 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one protein kinase domain, liver and testis, lung, which houses over 1, 400 genes and comprises nearly 8% of the human genome, The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DCHT SPAK |
| Also known as: |
STK39 Polyclonal Antibody |
| Other name: |
Anti-STK39 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
STK39 |
| Short name: |
Anti-STK39 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-STK39 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17717 |
| Gene: |
STK39 |
More about : STK39 |
| Long gene name: |
serine/threonine kinase 39 |
| Synonyms gene name: |
serine threonine kinase 39 |
| Synonyms name: |
STE20/SPS1 homolog (yeast) |
| Locus: |
2q24, 3 |
| Discovery year: |
2002-01-14 |
| GenBank acession: |
AF099989 |
| Entrez gene record: |
27347 |
| Pubmed identfication: |
10980603 |
| RefSeq identity: |
NM_013233 |
| Havana BLAST/BLAT: |
OTTHUMG00000133745 |