| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SRPK1 |
| Specificity: |
This antibody reacts specifically with SRPK1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SRPK1 |
| Gene ID: |
6732 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids, Hyperphosphorylates RS domain-containing proteins such as SFRS1, Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis, Plays a central role in the regulatory network for splicing |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SFRSK1 |
| Also known as: |
SRPK1 Polyclonal Antibody |
| Other name: |
Anti-SRPK1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SRPK1 |
| Short name: |
Anti-SRPK1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SRSF protein kinase 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
SFRSK1, SRPK1 and IDBG-629997 and ENSBTAG00000016838 and 512631, SRPK1 and IDBG-84414 and ENSG00000096063 and 6732, Srpk1 and IDBG-158718 and ENSMUSG00000004865 and 20815, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006397 and mRNA processing and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007059 and chromosome segregation and biological process this GO :0008380 and RNA splicing and biological process this GO :0016032 and viral process and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0044822 : poly(A) RNA binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0044822 : poly(A) RNA binding, transferring phosphorus-containing groups and molecular function this GO :0035092 and sperm chromatin condensation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0048024 and regulation of mRNA splicing, via spliceosome and biological process this GO :0050684 and regulation of mRNA processing and biological process, SRSF protein kinase 1 |
| Identity: |
11305 |
| Gene: |
SRPK1 |
More about : SRPK1 |
| Long gene name: |
SRSF protein kinase 1 |
| Synonyms gene name: |
SFRS protein kinase 1 |
| Synonyms name: |
SR protein kinase 1 serine/arginine-rich splicing factor kinase 1 |
| Locus: |
6p21, 31 |
| Discovery year: |
1998-03-02 |
| GenBank acession: |
U09564 |
| Entrez gene record: |
6732 |
| Pubmed identfication: |
8208298 10198174 |
| RefSeq identity: |
NM_003137 |
| Havana BLAST/BLAT: |
OTTHUMG00000014583 |