| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TREM2 |
| Specificity: |
This antibody reacts specifically with TREM2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TREM2 |
| Gene ID: |
54209 |
| Swiss Prot: |
Q9NZC2 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells, May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TREM-2 Trem2a Trem2b Trem2c |
| Also known as: |
TREM2 Polyclonal Antibody |
| Other name: |
Anti-TREM2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TREM2 |
| Short name: |
Anti-TREM2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-triggering receptor expressed on myeloid cells 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, TREM2 and IDBG-630863 and ENSBTAG00000007275 and 506467, TREM2 and IDBG-86566 and ENSG00000095970 and 54209, Trem2 and IDBG-189871 and ENSMUSG00000023992 and 83433, scaffold protein binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0002588 and positive regulation of antigen processing and presentation of peptide antigen via MHC class II and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006959 and humoral immune response and biological process this GO :0007411 and axon guidance and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045087 and innate immune response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0097028 and dendritic cell differentiation and biological process this GO :0097110 and scaffold protein binding and molecular function this GO :1903078 and positive regulation of protein localization to plasma membrane and biological process this GO :1903082 and positive regulation of C-C chemokine receptor CCR7 signaling pathway and biological process this GO :2000350 and positive regulation of CD40 signaling pathway and biological process, this GO :0001530 : lipopolysaccharide binding, this GO :0001530 : lipopolysaccharide binding and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0097110 : scaffold protein binding, this GO :0004872 : receptor activity, this GO :0005515 : protein binding, this GO :0097110 : scaffold protein binding, triggering receptor expressed on myeloid cells 2 |
| Identity: |
17761 |
| Gene: |
TREM2 |
More about : TREM2 |
| Long gene name: |
triggering receptor expressed on myeloid cells 2 |
| Synonyms gene name: |
triggering receptor expressed on myeloid cells 2a |
| Locus: |
6p21, 1 |
| Discovery year: |
2002-08-09 |
| GenBank acession: |
AF213457 |
| Entrez gene record: |
54209 |
| Pubmed identfication: |
10799849 12080485 |
| RefSeq identity: |
NM_018965 |
| Classification: |
V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000014671 |
| Locus Specific Databases: |
LRG_631 |