| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NGR2 |
| Specificity: |
This antibody reacts specifically with IFNGR2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IFNGR2 |
| Gene ID: |
3460 |
| Swiss Prot: |
P38484 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
JAK1, Required for signal transduction, This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, and/or JAK2, Part of the receptor for interferon gamma |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AF-1 |
| Also known as: |
IFNGR2 Polyclonal Antibody |
| Other name: |
Anti-IFNGR2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IFNGR2 |
| Short name: |
Anti-IFNGR2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-interferon g receptor 2 (interferon g transducer 1) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AF-1 and IFGR2 and IFNGT1 and IMD28, IFNGR2 and IDBG-2140 and ENSG00000159128 and 3460, IFNGR2 and IDBG-629818 and ENSBTAG00000012899 and 514889, Ifngr2 and IDBG-176102 and ENSMUSG00000022965 and 15980, Plasma membranes, protein binding, this GO :0004906 and interferon-gamma receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0009615 and response to virus and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process, this GO :0004906 : interferon-gamma receptor activity, this GO :0004906 : interferon-gamma receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, interferon gamma receptor 2 (interferon gamma transducer 1) |
| Identity: |
5440 |
| Gene: |
IFNGR2 |
More about : IFNGR2 |
| Long gene name: |
interferon gamma receptor 2 |
| Synonyms gene: |
IFNGT1 |
| Synonyms gene name: |
interferon gamma receptor 2 (interferon gamma transducer 1) |
| Locus: |
21q22, 11 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
3460 |
| Pubmed identfication: |
3136170 |
| Classification: |
Interferon receptors Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000065188 |
| Locus Specific Databases: |
IFNGR2base: Mutation registry for IFN&, #947, 2-receptor deficiency LRG_67 |