| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CD112 |
| Specificity: |
This antibody reacts specifically with CD112 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane, Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human nectin 2 |
| Gene ID: |
5819 |
| Swiss Prot: |
Q92692 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternate transcriptional splice variants, Can form trans-heterodimers with PVRL3/nectin-3, It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, This protein is one of the plasma membrane components of adherens junctions, Variations in this gene have been associated with differences in the severity of multiple sclerosis, and it is involved in cell to cell spreading of these viruses, encoding different isoforms, have been characterized, Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PVRR2 PRR2 CD112 |
| Also known as: |
CD112 Polyclonal Antibody |
| Other name: |
Anti-CD112 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CD112 |
| Short name: |
Anti-CD112 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CD112 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9707 |
| Gene: |
NECTIN2 |
More about : NECTIN2 |
| Long gene name: |
nectin cell adhesion molecule 2 |
| Synonyms gene: |
HVEB PVRL2 |
| Synonyms gene name: |
poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| Locus: |
19q13, 32 |
| Discovery year: |
1999-11-15 |
| GenBank acession: |
X80038 |
| Entrez gene record: |
5819 |
| Pubmed identfication: |
7622062 10196354 |
| RefSeq identity: |
NM_002856 |
| Classification: |
C2-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180839 |