| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Mouse (Mus musculus) |
| Target Protein/Peptide: |
TSHB |
| Specificity: |
This antibody reacts specifically with TSHB |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TSHB |
| Gene ID: |
7252 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rabbit, Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Each of these hormones also has a unique beta subunit, Free alpha and beta subunits have essentially no biological activity, In other words, TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another, TSH is composed of alpha subunit bound to the TSH beta subunit, The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, also known as thyrotropin, and, and TSH associates only with its own receptor, and stimulates that gland to synthesize and release thyroid hormones, finds its receptors on epithelial cells in the thyroid gland, follicle stimulating hormone and luteinizing hormone, in primates, in the placental hormone chorionic gonadotropin, is secreted from cells in the anterior pituitary called thyrotrophs, which provides receptor specificity, Thyroid stimulating hormone |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
TSHB Polyclonal Antibody |
| Other name: |
Anti-TSHB Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TSHB |
| Short name: |
Anti-TSHB (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TSHB (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12372 |
| Gene: |
TSHB |
More about : TSHB |
| Long gene name: |
thyroid stimulating hormone beta |
| Locus: |
1p13, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC069298 |
| Entrez gene record: |
7252 |
| Pubmed identfication: |
2457586 3243440 |
| RefSeq identity: |
NM_000549 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000011881 |