| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SPHK2 |
| Specificity: |
This antibody reacts specifically with SPHK2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SPHK2 |
| Gene ID: |
56848 |
| Swiss Prot: |
Q9NRA0 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also acts on D-erythro-dihydrosphingosine, Binds phosphoinositides, D-erythro-sphingosine and L-threo-dihydrosphingosine, a lipid mediator with both intra- and extracellular functions, Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
SPHK2 Polyclonal Antibody |
| Other name: |
Anti-SPHK2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SPHK2 |
| Short name: |
Anti-SPHK2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-sphin this GO sine kinase 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
D-erythro-sphin this GO sine kinase activity, Plasma membranes, SPHK2 and IDBG-60754 and ENSG00000063176 and 56848, SPHK2 and IDBG-640229 and ENSBTAG00000009872 and 533103, Sphk2 and IDBG-184179 and ENSMUSG00000057342 and 56632, this GO :0001568 and blood vessel development and biological process this GO :0003951 and NAD+ kinase activity and molecular function this GO :0004143 and diacylglycerol kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005765 and lysosomal membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006665 and sphin this GO lipid metabolic process and biological process this GO :0006669 and sphinganine-1-phosphate biosynthetic process and biological process this GO :0006670 and sphin this GO sine metabolic process and biological process this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007420 and brain development and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008481 and sphinganine kinase activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016310 and phosphorylation and biological process this GO :0017016 and Ras GTPase binding and molecular function this GO :0017050 and D-erythro-sphin this GO sine kinase activity and molecular function this GO :0030148 and sphin this GO lipid biosynthetic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046834 and lipid phosphorylation and biological process, this GO :0003951 : NAD+ kinase activity, this GO :0003951 : NAD+ kinase activity and also this GO :0004143 : diacylglycerol kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008481 : sphinganine kinase activity and also this GO :0017016 : Ras GTPase binding and also this GO :0017050 : D-erythro-sphin this GO sine kinase activity, this GO :0004143 : diacylglycerol kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008481 : sphinganine kinase activity, this GO :0017016 : Ras GTPase binding, this GO :0017050 : D-erythro-sphin this GO sine kinase activity, sphin this GO sine kinase 2 |
| Identity: |
18859 |
| Gene: |
SPHK2 |
More about : SPHK2 |
| Long gene name: |
sphingosine kinase 2 |
| Locus: |
19q13, 33 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF245447 |
| Entrez gene record: |
56848 |
| Pubmed identfication: |
10751414 17895250 |
| Havana BLAST/BLAT: |
OTTHUMG00000183318 |