| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IL17RA/CD217 |
| Specificity: |
This antibody reacts specifically with IL17RA/CD217 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IL17R |
| Gene ID: |
23765 |
| Swiss Prot: |
Q96F46 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds its IL17A ligand with low affinity, IL17F and, for IL17C, in dimer with IL17RE, suggesting that additional components are involved in IL17A-induced signaling, Receptor for IL17A |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
hIL-17R IL-17RA CDw217 CD217 |
| Also known as: |
IL17RA/CD217 Polyclonal Antibody |
| Other name: |
Anti-IL17RA/CD217 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IL17RA/CD217 |
| Short name: |
Anti-IL17RA/CD217 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-interleukin 17 receptor A/CD217 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CANDF5 and CD217 and CDw217 and hIL-17R and IL-17RA and IL17R, Extracellular, IL17RA and IDBG-641259 and ENSBTAG00000011067 and 525040, IL17RA and IDBG-885 and ENSG00000177663 and 23765, Il17ra and IDBG-183749 and ENSMUSG00000002897 and 16172, interleukin-17 receptor activity, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030368 and interleukin-17 receptor activity and molecular function this GO :0032747 and positive regulation of interleukin-23 production and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :0072537 and fibroblast activation and biological process this GO :1900017 and positive regulation of cytokine production involved in inflammatory response and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0030368 : interleukin-17 receptor activity, this GO :0030368 : interleukin-17 receptor activity, interleukin 17 receptor A |
| Identity: |
5985 |
| Gene: |
IL17RA |
More about : IL17RA |
| Long gene name: |
interleukin 17 receptor A |
| Synonyms gene: |
IL17R |
| Synonyms gene name: |
interleukin 17 receptor |
| Locus: |
22q11, 1 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
U58917 |
| Entrez gene record: |
23765 |
| Pubmed identfication: |
9367539 10591208 |
| RefSeq identity: |
NM_014339 |
| Classification: |
CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150026 |
| Locus Specific Databases: |
LRG_355 |