| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IL12RB2 |
| Specificity: |
This antibody reacts specifically with IL12RB2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IL-12RB2 |
| Gene ID: |
3595 |
| Swiss Prot: |
Q99665 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production, Promotes the proliferation of T-cells as well as NK cells, This subunit is the signaling component coupling to the JAK2/STAT4 pathway, Receptor for interleukin-12 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
IL12RB2 Polyclonal Antibody |
| Other name: |
Anti-IL12RB2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IL12RB2 |
| Short name: |
Anti-IL12RB2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, b 2 (polyclonal), antibody to-interleukin 12 receptor |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cell surfaces, IL12RB2 and IDBG-638111 and ENSBTAG00000009455 and 282452, IL12RB2 and IDBG-99563 and ENSG00000081985 and 3595, Il12rb2 and IDBG-153874 and ENSMUSG00000018341 and 16162, beta 2, protein kinase binding, this GO :0004896 and cytokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0034097 and response to cytokine and biological process, this GO :0004896 : cytokine receptor activity, this GO :0004896 : cytokine receptor activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, interleukin 12 receptor |
| Identity: |
5972 |
| Gene: |
IL12RB2 |
More about : IL12RB2 |
| Long gene name: |
interleukin 12 receptor subunit beta 2 |
| Synonyms gene name: |
beta 2 , interleukin 12 receptor |
| Locus: |
1p31, 3 |
| Discovery year: |
1997-02-10 |
| GenBank acession: |
U64198 |
| Entrez gene record: |
3595 |
| Pubmed identfication: |
9284929 8943050 |
| RefSeq identity: |
NM_001559 |
| Classification: |
Fibronectin type III domain containing Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000009094 |