| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IL10RB |
| Specificity: |
This antibody reacts specifically with IL10RB |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IL10RB |
| Gene ID: |
3588 |
| Swiss Prot: |
Q08334 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
IL22, IL26, IL28, The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity, The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), and IFNL1, which contribute to the antiviral state, Shared cell surface receptor required for the activation of five class 2 cytokines: IL10 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CRF2-4 CDW210B IL-10R2 |
| Also known as: |
IL10RB Polyclonal Antibody |
| Other name: |
Anti-IL10RB Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IL10RB |
| Short name: |
Anti-IL10RB (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, b (polyclonal), antibody to-interleukin 10 receptor |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CDW210B and CRF2-4 and CRFB4 and D21S58 and D21S66 and IL-10R2, IL10RB and IDBG-401888 and ENSG00000243646 and 3588, Plasma membranes, beta, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0004920 and interleukin-10 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032002 and interleukin-28 receptor complex and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004920 : interleukin-10 receptor activity and also this GO :0005515 : protein binding, this GO :0004920 : interleukin-10 receptor activity, this GO :0005515 : protein binding, interleukin 10 receptor |
| Identity: |
5965 |
| Gene: |
IL10RB |
More about : IL10RB |
| Long gene name: |
interleukin 10 receptor subunit beta |
| Synonyms gene: |
CRFB4 D21S58 D21S66 |
| Synonyms gene name: |
beta , interleukin 10 receptor |
| Locus: |
21q22, 11 |
| Discovery year: |
1993-04-06 |
| GenBank acession: |
U08988 |
| Entrez gene record: |
3588 |
| Pubmed identfication: |
8314576 9312047 |
| Classification: |
CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000065128 |
| Locus Specific Databases: |
LRG_152 |