| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cytochrome P450 1A2 |
| Specificity: |
This antibody reacts specifically with Cytochrome P450 1A2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Cytochrome P450 1A2 |
| Gene ID: |
1544 |
| Swiss Prot: |
P05177 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also acts in the metabolism of aflatoxin B1 and acetaminophen, Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation, Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin, In liver microsomes, It oxidizes a variety of structurally unrelated compounds, Most active in catalyzing 2-hydroxylation, Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines, and xenobiotics, fatty acids, including steroids, this enzyme is involved in an NADPH-dependent electron transport pathway, Cytochromes P450 are a group of heme-thiolate monooxygenases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CYP1A2, CYPIA2, Cytochrome P(3)450, Cytochrome P450 1A2, Cytochrome P450 4, Cytochrome P450-P3, P3-450, P450(PA), CP12 |
| Also known as: |
Cytochrome P450 1A2 Polyclonal Antibody |
| Other name: |
Anti-Cytochrome P450 1A2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Cytochrome P450 1A2 |
| Short name: |
Anti-Cytochrome P450 1A2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cytochrome P450 1A2 (polyclonal) |
| Alternative technique: |
polyclonals |