| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CD58/LFA-3 |
| Specificity: |
This antibody reacts specifically with CD58/LFA-3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CD58 |
| Gene ID: |
965 |
| Swiss Prot: |
P19256 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In addition, This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells, Ligand of the T-lymphocyte CD2 glycoprotein |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
CD58/LFA-3 Polyclonal Antibody |
| Other name: |
Anti-CD58/LFA-3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CD58/LFA-3 |
| Short name: |
Anti-CD58/LFA-3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CD58 molecule/LFA-3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CD58 and IDBG-101394 and ENSG00000116815 and 965, CD58 and IDBG-634482 and ENSBTAG00000040131 and 782186, Cell surfaces, ag3 and LFA-3 and LFA3, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :2000484 and positive regulation of interleukin-8 secretion and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, CD58 molecule |
| Identity: |
1688 |
| Gene: |
CD58 |
More about : CD58 |
| Long gene name: |
CD58 molecule |
| Synonyms gene: |
LFA3 |
| Synonyms gene name: |
(lymphocyte function-associated antigen 3) , CD58 antigen |
| Locus: |
1p13, 1 |
| Discovery year: |
1989-04-06 |
| GenBank acession: |
BC005930 |
| Entrez gene record: |
965 |
| Pubmed identfication: |
9510189 |
| RefSeq identity: |
NM_001779 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000022749 |