| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TNFRSF12A |
| Specificity: |
This antibody reacts specifically with TNFRSF12A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TNFRSF12A |
| Gene ID: |
51330 |
| Swiss Prot: |
Q9NP84 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
May modulate cellular adhesion to matrix proteins, Promotes angiogenesis and the proliferation of endothelial cells, Weak inducer of apoptosis in some cell types, Receptor for TNFSF12/TWEAK |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FN14 TweakR CD266 |
| Also known as: |
TNFRSF12A Polyclonal Antibody |
| Other name: |
Anti-TNFRSF12A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TNFRSF12A |
| Short name: |
Anti-TNFRSF12A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 12A (polyclonal), antibody to-tumor necrosis factor receptor superfamily |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, Cell surfaces, TNFRSF12A and IDBG-11328 and ENSG00000006327 and 51330, Tnfrsf12a and IDBG-143687 and ENSMUSG00000023905 and 27279, cell attachment to substrate and biological process this GO :0007155 and cell adhesion and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0045773 and positive regulation of axon extension and biological process this GO :0061041 and regulation of wound healing and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, member 12A, protein binding, this GO :0001525 and angiogenesis and biological process this GO :0001726 and ruffle and cellular component this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006931 and substrate-dependent cell migration, this GO :0005515 : protein binding, this GO :0005515 : protein binding, 20111 and IDBG-635818 and ENSBTAG00000012082 and 617439, tumor necrosis factor receptor superfamily |
| Identity: |
18152 |
| Gene: |
TNFRSF12A |
More about : TNFRSF12A |
| Long gene name: |
TNF receptor superfamily member 12A |
| Synonyms gene name: |
member 12A , tumor necrosis factor receptor superfamily |
| Locus: |
16p13, 3 |
| Discovery year: |
2002-12-20 |
| GenBank acession: |
AB035480 |
| Pubmed identfication: |
10751351 10551889 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000129001 |