| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CCL4 |
| Specificity: |
This antibody reacts specifically with CCL4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse CCL4 |
| Gene ID: |
6351 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A signal transducing receptor designated the CC chemokine receptor 1 (CC CKR1) with seven transmembrane domains that binds MIP1 alpha, B cells, G26, HC21, HIMAP, Human MIP1 beta refers to the products of several independently cloned cDNAs, MCP1 and RANTES with varying affinities has been isolated, MIP1 beta, MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha, MIP1 proteins are expressed primarily in T cells, PAT 744, The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta, and MAD 5a, and monocytes after antigen or mitogen stimulation, hH400, including Act2, respectively, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MIP-1-beta Act-2 AT744, 1 |
| Also known as: |
CCL4 Polyclonal Antibody |
| Other name: |
Anti-CCL4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CCL4 |
| Short name: |
Anti-CCL4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CCL4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
10630 |
| Gene: |
CCL4 |
More about : CCL4 |
| Long gene name: |
C-C motif chemokine ligand 4 |
| Synonyms gene: |
LAG1 SCYA4 |
| Synonyms gene name: |
small inducible cytokine A4 (homologous to mouse Mip-1b) chemokine (C-C motif) ligand 4 |
| Locus: |
17q12 |
| Discovery year: |
1990-07-05 |
| GenBank acession: |
M23502 |
| Entrez gene record: |
6351 |
| Pubmed identfication: |
1972563 |
| RefSeq identity: |
NM_002984 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000188414 |