| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APJ Receptor |
| Specificity: |
This antibody reacts specifically with APJ Receptor |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Apelin receptor |
| Gene ID: |
187 |
| Swiss Prot: |
P35414 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone, Alternative coreceptor with CD4 for HIV-1 infection, and heart failure, heart contractility, may be involved in the development of AIDS dementia, Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ90771 APJ APJR |
| Also known as: |
APJ Receptor Polyclonal Antibody |
| Other name: |
Anti-APJ Receptor Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APJ Receptor |
| Short name: |
Anti-APJ Receptor (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-APJ Receptor (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
339 |
| Gene: |
APLNR |
More about : APLNR |
| Long gene name: |
apelin receptor |
| Synonyms gene: |
AGTRL1 |
| Synonyms gene name: |
angiotensin II receptor-like 1 |
| Synonyms name: |
APJ (apelin) receptor |
| Locus: |
11q12, 1 |
| Discovery year: |
1994-07-07 |
| GenBank acession: |
U03642 |
| Entrez gene record: |
187 |
| Pubmed identfication: |
8294032 14622440 |
| RefSeq identity: |
NM_005161 |
| Classification: |
Peptide receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000167021 |