| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Dysferlin |
| Specificity: |
This antibody reacts specifically with Dysferlin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Dysferlin |
| Gene ID: |
8291 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing results in multiple transcript variants, Aug 2008], In addition, It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy, [provided by RefSeq, a skeletal muscle membrane protein which is important in the formation of caveolae, suggesting that it may be involved in membrane regeneration and repair, the protein encoded by this gene binds caveolin-3, The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FER1L1 |
| Also known as: |
Dysferlin Polyclonal Antibody |
| Other name: |
Anti-Dysferlin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Dysferlin |
| Short name: |
Anti-Dysferlin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Dysferlin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3097 |
| Gene: |
DYSF |
More about : DYSF |
| Long gene name: |
dysferlin |
| Synonyms gene: |
LGMD2B |
| Synonyms gene name: |
limb girdle muscular dystrophy 2B (autosomal recessive) |
| Synonyms name: |
fer-1-like family member 1 |
| Locus: |
2p13, 2 |
| Discovery year: |
1994-03-24 |
| GenBank acession: |
AF075575 |
| Entrez gene record: |
8291 |
| Pubmed identfication: |
8320700 |
| RefSeq identity: |
NM_003494 |
| Classification: |
Ferlin family |
| Havana BLAST/BLAT: |
OTTHUMG00000129757 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_845 |