| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
KIR2DL1 |
| Specificity: |
This antibody reacts specifically with KIR2DL1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CD158a/KIR2DL1 |
| Gene ID: |
3802 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It inhibits the activity of NK cells thus preventing cell lysis, KIR2DL1 is a receptor on human NK cells for HLA-C alleles, The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on natural killer (NK) cells and a subset of human T cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
cl-42 nkat1 47, 1 CD158A , 11 p58 |
| Also known as: |
KIR2DL1 Polyclonal Antibody |
| Other name: |
Anti-KIR2DL1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
KIR2DL1 |
| Short name: |
Anti-KIR2DL1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
1 (polyclonal), ALEXA Fluor 594, large cytoplasmic tail, two domains, antibody to-killer cellular immunoglobulin-like receptor |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
1, CD158A and KIR-K64 and KIR221 and NKAT and NKAT-1 and NKAT1 and p58, KIR2DL1 and IDBG-68931 and ENSG00000125498 and 3802, Plasma membranes, long cytoplasmic tail, protein binding, this GO :0002769 and natural killer cell inhibitory signaling pathway and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0050776 and regulation of immune response and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, two domains, 1, killer cell immunoglobulin-like receptor |
| Identity: |
6329 |
| Gene: |
KIR2DL1 |
More about : KIR2DL1 |
| Long gene name: |
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 |
| Synonyms gene name: |
1 , killer cell immunoglobulin-like receptor, long cytoplasmic tail, two domains |
| Locus: |
19q13, 42 |
| Discovery year: |
1997-11-14 |
| GenBank acession: |
L41267 |
| Entrez gene record: |
3802 |
| Pubmed identfication: |
7749980 7716543 |
| RefSeq identity: |
NM_014218 |
| Classification: |
Killer cell immunoglobulin like receptors CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000065885 |
| Locus Specific Databases: |
IPD-KIR Database |