| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GEF H1 Ser886 |
| Specificity: |
This antibody reacts specifically with GEF H1 (Ser886) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser886 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886 |
| Gene ID: |
9181 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
This protein has also been shown to localize to tight junctions and modulate polarized cell permeability, GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GEF HDBP1 Si-1-2 Si-1-2-19 |
| Also known as: |
GEF H1 (Ser886) Polyclonal Antibody |
| Other name: |
Anti-GEF H1 (Ser886) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GEF H1 (Ser886) |
| Short name: |
Anti-GEF H1 (Ser886) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GEF H1 (Ser886) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
15930 |
| Gene: |
SLC2A4RG |
More about : SLC2A4RG |
| Long gene name: |
SLC2A4 regulator |
| Synonyms name: |
GLUT4 enhancer factor Huntington', s disease gene regulatory region-binding protein 1 |
| Locus: |
20q13, 33 |
| Discovery year: |
2001-06-21 |
| GenBank acession: |
AF249267 |
| Entrez gene record: |
56731 |
| Pubmed identfication: |
10825161 |
| RefSeq identity: |
NM_020062 |
| Havana BLAST/BLAT: |
OTTHUMG00000032997 |