| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NQO1 |
| Specificity: |
This antibody reacts specifically with NQO1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NQO1 |
| Gene ID: |
1728 |
| Swiss Prot: |
P15559 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DHQU QR1 DTD |
| Also known as: |
NQO1 Polyclonal Antibody |
| Other name: |
Anti-NQO1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NQO1 |
| Short name: |
Anti-NQO1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, quinone 1 (polyclonal), antibody to-Nicotinamide adenine dinucleotide(P)H dehydrogenase |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, DHQU and DIA4 and DTD and NMOR1 and NMORI and QR1, NQO1 and IDBG-39427 and ENSG00000181019 and 1728, NQO1 and IDBG-634590 and ENSBTAG00000020632 and 519632, Nqo1 and IDBG-190808 and ENSMUSG00000003849 and 18104, acting on NAD(P)H, acting on NAD(P)H and also this GO :0004784 : superoxide dismutase activity and also this GO :0005515 : protein binding and also this GO :0016491 : oxidoreductase activity and also this GO :0044822 : poly(A) RNA binding, acting on NAD(P)H and molecular function this GO :0004784 and superoxide dismutase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006801 and superoxide metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007271 and synaptic transmission, cholinergic and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0009636 and response to toxic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0019430 and removal of superoxide radicals and biological process this GO :0032355 and response to estradiol and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043086 and negative regulation of catalytic activity and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045471 and response to ethanol and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, cytochrome-b5 reductase activity, quinone 1, this GO :0003955 and NAD(P)H dehydrogenase (quinone) activity and molecular function this GO :0004128 and cytochrome-b5 reductase activity, this GO :0003955 : NAD(P)H dehydrogenase (quinone) activity, this GO :0003955 : NAD(P)H dehydrogenase (quinone) activity and also this GO :0004128 : cytochrome-b5 reductase activity, this GO :0004128 : cytochrome-b5 reductase activity, this GO :0004784 : superoxide dismutase activity, this GO :0005515 : protein binding, this GO :0016491 : oxidoreductase activity, this GO :0044822 : poly(A) RNA binding, NAD(P)H dehydrogenase |
| Identity: |
2874 |
| Gene: |
NQO1 |
More about : NQO1 |
| Long gene name: |
NAD(P)H quinone dehydrogenase 1 |
| Synonyms gene: |
NMOR1 DIA4 |
| Synonyms gene name: |
diaphorase (NADH/NADPH) (cytochrome b-5 reductase) NAD(P)H dehydrogenase, quinone 1 |
| Locus: |
16q22, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M81600 |
| Entrez gene record: |
1728 |
| Pubmed identfication: |
2843525 |
| Havana BLAST/BLAT: |
OTTHUMG00000137575 |