| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Noelin |
| Specificity: |
This antibody reacts specifically with Noelin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Noelin |
| Gene ID: |
10439 |
| Swiss Prot: |
Q99784 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG), OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, OLFM2 (Noelin-2), OLFM2 participates in the regulation of the development of the anterior nervous system, OLFM3 (Noelin-3), OLFM4 (Noelin-4), Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production, Specifically, These proteins are implicated in the development of the nervous system, and later in brain tissue and in the zone of polarizing activity in the limb, as well as in the cranial ganglia in mouse at E8-10, gliomedin and mycocilin, pancortin, tiarin, which includes OLFM1 (Noelin-1), The Olfactomedin family comprises a diverse group of secreted glycoproteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NOE1 OlfA AMY NOELIN |
| Also known as: |
Noelin Polyclonal Antibody |
| Other name: |
Anti-Noelin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Noelin |
| Short name: |
Anti-Noelin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Noelin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17187 |
| Gene: |
OLFM1 |
More about : OLFM1 |
| Long gene name: |
olfactomedin 1 |
| Synonyms name: |
pancortin noelin |
| Locus: |
9q34, 3 |
| Discovery year: |
2001-12-12 |
| GenBank acession: |
AF035301 |
| Entrez gene record: |
10439 |
| Pubmed identfication: |
9039501 |
| RefSeq identity: |
NM_014279 |
| Havana BLAST/BLAT: |
OTTHUMG00000020897 |