| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
KLK9 |
| Specificity: |
This antibody reacts specifically with KLK9 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human KLK9 |
| Gene ID: |
284366 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Different splice variants of hK9 have been reported, Kallikrein 9 has been found in the ovary, Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins, Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, The 234 amino acid form predicts a protein of 26 kDa with a pI of 9, The full length Kallikrein 9 encodes for a 250 amino acid protein, The shorter sequence also diverges before the catalytic serine residue, also known as Kallikrein-Like 3 (KLK-L3), although it is not yet known if they produce functional proteins, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain, breast and neuronal tissues and is made by many cell lines in culture, is a chymotrypsin-like serine proteinase, making it unlikely to be proteolytically active, prostate, skin, testis, thus hK9 might be considered a favorable prognostic marker, thymus, with a predicted mass of 27, 5 kDa and a pI of 7, 53, 76 and this quite basic pI might give the shorter form a very different function or localization, Kallikrein 9 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KLK-L3 |
| Also known as: |
KLK9 Polyclonal Antibody |
| Other name: |
Anti-KLK9 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
KLK9 |
| Short name: |
Anti-KLK9 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-KLK9 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6370 |
| Gene: |
KLK9 |
More about : KLK9 |
| Long gene name: |
kallikrein related peptidase 9 |
| Synonyms gene name: |
kallikrein 9 |
| Locus: |
19q13, 33 |
| Discovery year: |
2000-03-16 |
| GenBank acession: |
AF135026 |
| Entrez gene record: |
284366 |
| Pubmed identfication: |
16800724 16800723 |
| RefSeq identity: |
NM_012315 |
| Classification: |
Kallikreins |
| Havana BLAST/BLAT: |
OTTHUMG00000183087 |