| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PLAUR |
| Specificity: |
This antibody reacts specifically with PLAUR |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PLAUR |
| Gene ID: |
5329 |
| Swiss Prot: |
Q03405 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form, Mediates the proteolysis-independent signal transduction activation effects of U-PA, Plays a role in localizing and promoting plasmin formation, Acts as a receptor for urokinase plasminogen activator |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
URKR UPAR CD87 |
| Also known as: |
PLAUR Polyclonal Antibody |
| Other name: |
Anti-PLAUR Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PLAUR |
| Short name: |
Anti-PLAUR (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, urokinase receptor (polyclonal), antibody to-plasminogen activator |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CD87 and U-PAR and UPAR and URKR, DNA-templated and biological process this GO :0006501 and C-terminal protein lipidation and biological process this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016255 and attachment of GPI anchor to protein and biological process this GO :0019898 and extrinsic component of membrane and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030162 and regulation of proteolysis and biological process this GO :0030377 and U-plasminogen activator receptor activity and molecular function this GO :0031225 and anchored component of membrane and cellular component this GO :0038195 and urokinase plasminogen activator signaling pathway and biological process this GO :0042730 and fibrinolysis and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, PLAUR and IDBG-55442 and ENSG00000011422 and 5329, PLAUR and IDBG-639118 and ENSBTAG00000013125 and 281983, Plaur and IDBG-154827 and ENSMUSG00000046223 and 18793, U-plasminogen activator receptor activity, nuclei, this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019899 : enzyme binding and also this GO :0030377 : U-plasminogen activator receptor activity, this GO :0004872 : receptor activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0019899 : enzyme binding, this GO :0030377 : U-plasminogen activator receptor activity, urokinase receptor, plasminogen activator |
| Identity: |
9053 |
| Gene: |
PLAUR |
More about : PLAUR |
| Long gene name: |
plasminogen activator, urokinase receptor |
| Synonyms name: |
urokinase-type plasminogen activator (uPA) receptor urokinase plasminogen activator surface receptor |
| Locus: |
19q13 |
| Discovery year: |
1991-06-05 |
| Entrez gene record: |
5329 |
| RefSeq identity: |
NM_002659 |
| Classification: |
CD molecules LY6/PLAUR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182778 |