| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PTGEs |
| Specificity: |
This antibody reacts specifically with PTGEs |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Helical |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PTGEs |
| Gene ID: |
9536 |
| Swiss Prot: |
O14684 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is a member of the MAPEG family, It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses, Its expression can also be induced by tumor suppressor protein TP53, Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses, The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B), and may be involved in TP53 induced apoptosis, Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2, The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGST-IV PIG12 MGST1-L1 TP53I12 |
| Also known as: |
PTGEs Polyclonal Antibody |
| Other name: |
Anti-PTGEs Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PTGEs |
| Short name: |
Anti-PTGEs (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-prostaglandin E synthase (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9599 |
| Gene: |
PTGES |
More about : PTGES |
| Long gene name: |
prostaglandin E synthase |
| Synonyms gene: |
MGST1L1 |
| Synonyms name: |
microsomal glutathione S-transferase 1-like 1 tumor protein p53 inducible protein 12 p53-induced gene 12 microsomal prostaglandin E synthase-1 glutathione S-transferase 1-like 1 MGST1-like 1 |
| Locus: |
9q34, 11 |
| Discovery year: |
1999-05-06 |
| GenBank acession: |
AF010316 |
| Entrez gene record: |
9536 |
| Pubmed identfication: |
9305847 10091672 |
| RefSeq identity: |
NM_004878 |
| Havana BLAST/BLAT: |
OTTHUMG00000020791 |