| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
KCNH2 |
| Specificity: |
This antibody reacts specifically with KCNH2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HERG |
| Gene ID: |
3757 |
| Swiss Prot: |
Q12809 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Dog, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Channel properties are modulated by cAMP and subunit assembly, Isoforms USO have no channel activity by themself, Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr), but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation, Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Kv11, 1 HERG erg1 |
| Also known as: |
KCNH2 Polyclonal Antibody |
| Other name: |
Anti-KCNH2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
KCNH2 |
| Short name: |
Anti-KCNH2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-KCNH2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6251 |
| Gene: |
KCNH2 |
More about : KCNH2 |
| Long gene name: |
potassium voltage-gated channel subfamily H member 2 |
| Synonyms gene: |
LQT2 |
| Synonyms gene name: |
member 2 , potassium voltage-gated channel, subfamily H (eag-related) |
| Locus: |
7q36, 1 |
| Discovery year: |
1993-03-22 |
| GenBank acession: |
U04270 |
| Entrez gene record: |
3757 |
| Pubmed identfication: |
18616963 7842012 8159766 16382104 |
| RefSeq identity: |
NM_000238 |
| Classification: |
Potassium voltage-gated channels |
| Havana BLAST/BLAT: |
OTTHUMG00000158341 |
| Locus Specific Databases: |
Gene Connection for the Heart KCNH2 database at LOVD-China LRG_288 |