| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ABCD1/CCL22 |
| Specificity: |
This antibody reacts specifically with ABCD1/CCL22 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse ABCD1 |
| Gene ID: |
6367 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes, It has no chemoattractant activity for eosinophils, The CC cytokines are proteins characterized by two adjacent cysteines, The cytokine encoded by MDC displays chemotactic activity for natural killer cells, The product of this gene binds to chemokine receptor CCR4, This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology, chronically activated T lymphocytes, monocytes and dendritic cells, neutrophils and resting T lymphocytes and also displays a mild activity for primary activated T lymphocytes, The MDC gene is one of several Cys-Cys (CC) cytokine genes which are clustered on the q arm of chromosome 16 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AMN ALDP adrenoleukodystrophy |
| Also known as: |
ABCD1/CCL22 Polyclonal Antibody |
| Other name: |
Anti-ABCD1/CCL22 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ABCD1/CCL22 |
| Short name: |
Anti-ABCD1/CCL22 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ABCD1/chemokine (C-C motif) ligand 22 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ABCD-1 and DC/B-CK and MDC and SCYA22 and STCP-1, CCL22 and IDBG-33170 and ENSG00000102962 and 6367, CCL22 and IDBG-632465 and ENSBTAG00000017718 and 616996, Ccl22 and IDBG-182591 and ENSMUSG00000031779 and 20299, Extracellular, chemokine activity, this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0009615 and response to virus and biological process this GO :0060326 and cell chemotaxis and biological process, this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity, chemokine (C-C motif) ligand 22 |
| Identity: |
61 |
| Gene: |
ABCD1 |
More about : ABCD1 |
| Long gene name: |
ATP binding cassette subfamily D member 1 |
| Synonyms gene: |
ALD |
| Synonyms gene name: |
ATP-binding cassette, member 1 , sub-family D (ALD) |
| Locus: |
Xq28 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
Z21876 |
| Entrez gene record: |
215 |
| Pubmed identfication: |
8441467 6795626 |
| RefSeq identity: |
NM_000033 |
| Classification: |
ATP binding cassette subfamily D |
| Havana BLAST/BLAT: |
OTTHUMG00000024215 |
| Locus Specific Databases: |
X-linked Adrenoleukodystrophy Database Mental Retardation database LRG_1017 |