| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CX3CR1 |
| Specificity: |
This antibody reacts specifically with CX3CR1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CX3CR1 |
| Gene ID: |
1524 |
| Swiss Prot: |
P49238 |
| Applications: |
FCM |
| Applications with corresponding dilutions: |
FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1, Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CMKDR1 V28 CCRL1 |
| Also known as: |
CX3CR1 Polyclonal Antibody |
| Other name: |
Anti-CX3CR1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CX3CR1 |
| Short name: |
Anti-CX3CR1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-chemokine (C-X3-C motif) receptor 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
C-X3-C chemokine receptor activity, CCRL1 and CMKBRL1 and CMKDR1 and GPR13 and GPRV28 and V28, CX3CR1 and IDBG-26647 and ENSG00000168329 and 1524, CX3CR1 and IDBG-644403 and ENSBTAG00000002923 and 100124525, Cx3cr1 and IDBG-204952 and ENSMUSG00000052336 and 13051, Plasma membranes, this GO :0002282 and microglial cell activation involved in immune response and biological process this GO :0004896 and cytokine receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006968 and cellular defense response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0009611 and response to wounding and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016495 and C-X3-C chemokine receptor activity and molecular function this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0021795 and cerebral cortex cell migration and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0032809 and neuronal cell body membrane and cellular component this GO :0043005 and neuron projection and cellular component this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048246 and macrophage chemotaxis and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0004896 : cytokine receptor activity, this GO :0004896 : cytokine receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding and also this GO :0016495 : C-X3-C chemokine receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, this GO :0016495 : C-X3-C chemokine receptor activity, chemokine (C-X3-C motif) receptor 1 |
| Identity: |
2558 |
| Gene: |
CX3CR1 |
More about : CX3CR1 |
| Long gene name: |
C-X3-C motif chemokine receptor 1 |
| Synonyms gene: |
GPR13 CMKBRL1 |
| Synonyms gene name: |
chemokine (C-X3-C) receptor 1 chemokine (C-X3-C motif) receptor 1 |
| Locus: |
3p22, 2 |
| Discovery year: |
1998-01-12 |
| GenBank acession: |
BC028078 |
| Entrez gene record: |
1524 |
| Pubmed identfication: |
9726990 7646814 |
| RefSeq identity: |
NM_001337 |
| Classification: |
C-X-3-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000156249 |