| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CNR1/CB1 |
| Specificity: |
This antibody reacts specifically with CNR1/CB1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CNR-1 |
| Gene ID: |
1268 |
| Swiss Prot: |
P21554 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts by inhibiting adenylate cyclase, Could be a receptor for anandamide, Inhibits L-type Ca(2+) channel current, Isoform 2 and isoform 3 have altered ligand binding, Involved in cannabinoid-induced CNS effects |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CNR1 |
| Also known as: |
CNR1/CB1 Polyclonal Antibody |
| Other name: |
Anti-CNR1/CB1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CNR1/CB1 |
| Short name: |
Anti-CNR1/CB1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-cannabinoid receptor 1 (brain)/CB1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CANN6 and CB-R and CB1 and CB1A and CB1K5 and CB1R and CNR, CNR1 and IDBG-647973 and ENSBTAG00000046006 and 100299449, CNR1 and IDBG-94226 and ENSG00000118432 and 1268, Cnr1 and IDBG-134736 and ENSMUSG00000044288 and 12801, GABAergic and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033004 and negative regulation of mast cell activation and biological process this GO :0033602 and negative regulation of dopamine secretion and biological process this GO :0035094 and response to nicotine and biological process this GO :0042220 and response to cocaine and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043271 and negative regulation of ion transport and biological process this GO :0043278 and response to morphine and biological process this GO :0045471 and response to ethanol and biological process this GO :0045759 and negative regulation of action potential and biological process this GO :0045776 and negative regulation of blood pressure and biological process this GO :0045777 and positive regulation of blood pressure and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0051001 and negative regulation of nitric-oxide synthase activity and biological process this GO :0051966 and regulation of synaptic transmission, Plasma membranes, coupled to cyclic nucleotide second messenger and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0007611 and learning or memory and biological process this GO :0007613 and memory and biological process this GO :0008144 and drug binding and molecular function this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019216 and regulation of lipid metabolic process and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0031622 and positive regulation of fever generation and biological process this GO :0031999 and negative regulation of fatty acid beta-oxidation and biological process this GO :0032228 and regulation of synaptic transmission, drug binding, glutamatergic and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0060259 and regulation of feeding behavior and biological process this GO :0060405 and regulation of penile erection and biological process, this GO :0002866 and positive regulation of acute inflammatory response to antigenic stimulus and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004949 and cannabinoid receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004949 : cannabinoid receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding, this GO :0004949 : cannabinoid receptor activity, this GO :0005515 : protein binding, this GO :0008144 : drug binding, cannabinoid receptor 1 (brain) |
| Identity: |
8662 |
| Gene: |
PCDHA@ |
More about : PCDHA@ |
| Long gene name: |
complex locus , protocadherin alpha cluster |
| Synonyms gene: |
CNRS1 |
| Synonyms gene name: |
protocadherin alpha cluster |
| Locus: |
5q31 |
| Discovery year: |
1999-11-26 |
| Entrez gene record: |
56117 |
| Pubmed identfication: |
10662547 10380929 |
| Classification: |
Clustered protocadherins |