| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CIB1 |
| Specificity: |
This antibody reacts specifically with CIB1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CIB1 |
| Gene ID: |
10519 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CIB1(Calcium and integrin binding 1) may convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through the binding to the integrin cytoplasmic domain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SIP2-28 CIB KIP |
| Also known as: |
CIB1 Polyclonal Antibody |
| Other name: |
Anti-CIB1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CIB1 |
| Short name: |
Anti-CIB1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-calcium and integrin binding 1 (calmyrin) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CIB and CIBP and KIP1 and PRKDCIP and SIP2-28, CIB1 and IDBG-29930 and ENSG00000185043 and 10519, CIB1 and IDBG-629341 and ENSBTAG00000021275 and 510141, Cib1 and IDBG-194710 and ENSMUSG00000030538 and 23991, ion channel binding, nuclei, this GO :0001525 and angiogenesis and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002931 and response to ischemia and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005813 and centrosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006302 and double-strand break repair and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007026 and negative regulation of microtubule depolymerization and biological process this GO :0007113 and endomitotic cell cycle and biological process this GO :0007155 and cell adhesion and biological process this GO :0007286 and spermatid development and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0016020 and membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0017016 and Ras GTPase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030220 and platelet formation and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030426 and growth cone and cellular component this GO :0031122 and cytoplasmic microtubule organization and biological process this GO :0032433 and filopodium tip and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0033630 and positive regulation of cell adhesion mediated by integrin and biological process this GO :0038163 and thrombopoietin-mediated signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043495 and protein anchor and molecular function this GO :0044325 and ion channel binding and molecular function this GO :0045653 and negative regulation of megakaryocyte differentiation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048554 and positive regulation of metalloenzyme activity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051301 and cell division and biological process this GO :0051302 and regulation of cell division and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070886 and positive regulation of calcineurin-NFAT signaling cascade and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071902 and positive regulation of protein serine/threonine kinase activity and biological process this GO :0071944 and cell periphery and cellular component this GO :0090004 and positive regulation of establishment of protein localization to plasma membrane and biological process this GO :0090050 and positive regulation of cell migration involved in sprouting angiogenesis and biological process this GO :0090314 and positive regulation of protein targeting to membrane and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :1900026 and positive regulation of substrate adhesion-dependent cell spreading and biological process this GO :1901313 and positive regulation of gene expression involved in extracellular matrix organization and biological process this GO :1990090 and cellular response to nerve growth factor stimulus and biological process this GO :2000256 and positive regulation of male germ cell proliferation and biological process, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0017016 : Ras GTPase binding and also this GO :0043495 : protein anchor and also this GO :0044325 : ion channel binding, this GO :0005515 : protein binding, this GO :0017016 : Ras GTPase binding, this GO :0043495 : protein anchor, this GO :0044325 : ion channel binding, calcium and integrin binding 1 (calmyrin) |
| Identity: |
16920 |
| Gene: |
CIB1 |
More about : CIB1 |
| Long gene name: |
calcium and integrin binding 1 |
| Synonyms name: |
calmyrin |
| Locus: |
15q26, 1 |
| Discovery year: |
2002-05-08 |
| GenBank acession: |
U82226 |
| Entrez gene record: |
10519 |
| Pubmed identfication: |
9030514 10826701 |
| Classification: |
EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000149808 |