| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
XBP1 |
| Specificity: |
may also interact with chickenXBP1, XBP-1 antibody will recognize both isoforms |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human XBP-1 |
| Gene ID: |
7494 |
| Swiss Prot: |
P17861 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE), Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', Binds to the HLA DR-alpha promoter, Binds to the Tax-responsive element (TRE) of HTLV-I, and also to some TPA response elements (TRE), and the unfolded protein response (UPR), the differentiation of plasma cells, the immunoglobulin secretion, Transcription factor essential for hepatocyte growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
XBP1 Polyclonal Antibody |
| Other name: |
Anti-XBP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
XBP1 |
| Short name: |
Anti-XBP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-XBP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12801 |
| Gene: |
XBP1 |
More about : XBP1 |
| Long gene name: |
X-box binding protein 1 |
| Synonyms gene: |
XBP2 |
| Locus: |
22q12, 1 |
| Discovery year: |
1992-02-13 |
| GenBank acession: |
M31627 |
| Entrez gene record: |
7494 |
| Pubmed identfication: |
1718857 2196176 |
| RefSeq identity: |
NM_005080 |
| Classification: |
Basic leucine zipper proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000151094 |