| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CCR-2B |
| Specificity: |
This antibody reacts specifically with CCR-2B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CCR-2B |
| Gene ID: |
1231 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, CCR2 is also an alternative coreceptor with CD4 for HIV1 infection, CCR2 transduces such signals by increasing the intracellular level of calcium ions, For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors, MCP3, MCP4) which specifically mediate monocyte chemotaxis, brain, heart, including blood, is a receptor for several monocyte chemo attractant proteins (MCP1, kidney, liver, lung, or C C chemokine receptor type 2, ovary, pancreas, spinal cord, spleen and thymus, CCR2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
C C CKR 2, C C chemokine receptor type 2, CC CKR 2, CC chemokine receptor type 2, CCCKR2, CCR 2, CCR1L, CCR2A, CCR2B, CCR5L, CD192, CD192 antigen, CKR 2, CKR2, CKR2A, CKR2B, CMKBR2, Chemokine C C mot receptor 2, Chemokine CC Mot Receptor 2, MCP 1 R, MCP1 RECEPTOR, MCP1R, Monocyte Chemotactic Protein 1 Receptor, Monocyte chemoattractant protein 1 receptor, C-C Chemokine receptor 2B |
| Also known as: |
CCR-2B Polyclonal Antibody |
| Other name: |
Anti-CCR-2B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CCR-2B |
| Short name: |
Anti-CCR-2B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CCR-2B (polyclonal) |
| Alternative technique: |
polyclonals |