| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Antithrombin III |
| Specificity: |
This antibody reacts specifically with Antithrombin III |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted, Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Antithrombin III |
| Gene ID: |
462 |
| Swiss Prot: |
P01008 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AT-III inhibits thrombin, Its inhibitory activity is greatly enhanced in the presence of heparin, Xa and XIa, as well as factors IXa, matriptase-3/TMPRSS7, Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ATIII MGC22579 |
| Also known as: |
Antithrombin III Polyclonal Antibody |
| Other name: |
Anti-Antithrombin III Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Antithrombin III |
| Short name: |
Anti-Antithrombin III (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Antithrombin III (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
775 |
| Gene: |
SERPINC1 |
More about : SERPINC1 |
| Long gene name: |
serpin family C member 1 |
| Synonyms gene: |
AT3 |
| Synonyms gene name: |
clade C (antithrombin), clade C (antithrombin), member 1 , member 1 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor |
| Synonyms name: |
antithrombin III signal peptide antithrombin part 1 coding sequence signal peptide antithrombin part 1 antithrombin (aa 375-432) |
| Locus: |
1q25, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X68793 |
| Entrez gene record: |
462 |
| Pubmed identfication: |
3979120 24172014 |
| RefSeq identity: |
NM_000488 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000037276 |
| Locus Specific Databases: |
Antithrombin III mutation database LRG_577 |