| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PSMD10 |
| Specificity: |
This antibody reacts specifically with PSMD10 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PSMD10 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Aberrant expression of this gene may paly a role in tumorigenesis, Pseudogenes have been identified on chromosomes 3 and 20, The 26S proteosome complex is required for ubiquitin-dependent protein degradation, This protein is a non-ATPase subunit that may be involved in protein-protein interactions, Two transcripts encoding different isoforms have been described, which is the regulatory component of the 26S proteasome, PSMD10 is a subunit of the PA700/19S complex |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p28 |
| Also known as: |
PSMD10 Polyclonal Antibody |
| Other name: |
Anti-PSMD10 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PSMD10 |
| Short name: |
Anti-PSMD10 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
10 (polyclonal), ALEXA Fluor 594, macropain) 26S subunit, non-ATPase, antibody to-proteasome (prosome |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
10, PSMD10 and IDBG-634094 and ENSBTAG00000013721 and 535414, PSMD10 and IDBG-81755 and ENSG00000101843 and 5716, Psmd10 and IDBG-175123 and ENSMUSG00000031429 and 53380, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005838 and proteasome regulatory particle and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, base subcomplex and cellular component this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043518 and negative regulation of DNA damage response, dJ889N15, macropain) 26S subunit, non-ATPase, nuclei, signal transduction by p53 class mediator and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045111 and intermediate filament cytoskeleton and cellular component this GO :0045737 and positive regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0070682 and proteasome regulatory particle assembly and biological process this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007253 and cytoplasmic sequestering of NF-kappaB and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008540 and proteasome regulatory particle, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding, this GO :0008134 : transcription factor binding, transcription factor binding, 2 and p28 and p28(GANK), proteasome (prosome |
| Identity: |
9555 |
| Gene: |
PSMD10 |
More about : PSMD10 |
| Long gene name: |
non-ATPase 10 , proteasome 26S subunit |
| Synonyms gene name: |
10 , macropain) 26S subunit, non-ATPase, proteasome (prosome |
| Synonyms name: |
gankyrin |
| Locus: |
Xq22, 3 |
| Discovery year: |
1997-02-19 |
| GenBank acession: |
AB009619 |
| Entrez gene record: |
5716 |
| Pubmed identfication: |
9714768 |
| RefSeq identity: |
NM_170750 |
| Classification: |
Ankyrin repeat domain containing Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000022177 |
| Locus Specific Databases: |
Mental Retardation database |