| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TEM8 |
| Specificity: |
This antibody reacts specifically with TEM8 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TEM8 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Oct 2008], Once inside the cell, The binding of the protective antigen (PA) component, The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, Three alternatively spliced variants that encode different protein isoforms have been described, [provided by RefSeq, anthrax, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes, of the tripartite anthrax toxin, the causative agent of the disease, the other two components of anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells, This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TEM8 FLJ21776 FLJ10601 ATR |
| Also known as: |
TEM8 Polyclonal Antibody |
| Other name: |
Anti-TEM8 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TEM8 |
| Short name: |
Anti-TEM8 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TEM8 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
21014 |
| Gene: |
ANTXR1 |
More about : ANTXR1 |
| Long gene name: |
anthrax toxin receptor 1 |
| Synonyms name: |
anthrax toxin receptor tumor endothelial marker 8 precursor |
| Locus: |
2p13, 3 |
| Discovery year: |
2003-08-27 |
| GenBank acession: |
AF421380 |
| Entrez gene record: |
84168 |
| Pubmed identfication: |
10947988 11559528 |
| RefSeq identity: |
NM_032208 |
| Havana BLAST/BLAT: |
OTTHUMG00000129575 |