| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IGFBPL1 |
| Specificity: |
This antibody reacts specifically with IGFBPL1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IGFBPL1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Highly expressed in both brain and testis, IGF-binding proteins characteristically act to extend the half-life of IGFs and may influence the growth promoting effects of the IGFs, IGFBPL1 has been found to be down-regulated in multiple tumors and thus may be a likely tumor suppressor candidate, IGFBPL1 is found at lower levels in the prostate, IGFBPs may enhance or decrease a cells insulin sensitivity, The interaction of IGFBPs with IGFs can affect cell surface receptors, an IGFBP N-terminal domain and a Kazal-like domain, bladder and lung, specifically, IGFBPL1 is a secreted IGF (Insulin-like growth factor) binding protein that is known to contain an Ig-like C2-type (immunoglobulin-like) domain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
bA113O24, 1 |
| Also known as: |
IGFBPL1 Polyclonal Antibody |
| Other name: |
Anti-IGFBPL1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IGFBPL1 |
| Short name: |
Anti-IGFBPL1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-IGFBPL1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
20081 |
| Gene: |
IGFBPL1 |
More about : IGFBPL1 |
| Long gene name: |
insulin like growth factor binding protein like 1 |
| Synonyms gene name: |
insulin-like growth factor binding protein-like 1 insulin like growth factor binding protein-like 1 |
| Locus: |
9p13, 1 |
| Discovery year: |
2004-04-16 |
| Entrez gene record: |
347252 |
| RefSeq identity: |
XM_294567 |
| Classification: |
I-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019937 |