| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ITM5 |
| Specificity: |
This antibody reacts specifically with IFITM5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IFITM5 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
22863195), A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, A similar gene, The mouse gene encodes a transmembrane protein described as participating in germ cell competence, This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, is a member of the interferon-inducible fragilis gene family, located in a gene cluster on mouse chromosome 7, this gene has not been shown to be interferon inducible, IFITM5 is a membrane protein thought to play a role in bone mineralization |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
fragilis4 Hrmp1 BRIL |
| Also known as: |
IFITM5 Polyclonal Antibody |
| Other name: |
Anti-IFITM5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IFITM5 |
| Short name: |
Anti-IFITM5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-interferon induced transmembrane protein 5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
IFITM5 and IDBG-16179 and ENSG00000206013 and 387733, IFITM5 and IDBG-641948 and ENSBTAG00000020575 and 526461, Ifitm5 and IDBG-211931 and ENSMUSG00000025489 and 73835, Plasma membranes, this GO :0005886 and plasma membrane and cellular component this GO :0009607 and response to biotic stimulus and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030282 and bone mineralization and biological process this GO :0030500 and regulation of bone mineralization and biological process, interferon induced transmembrane protein 5 |
| Identity: |
16644 |
| Gene: |
IFITM5 |
More about : IFITM5 |
| Long gene name: |
interferon induced transmembrane protein 5 |
| Locus: |
11p15, 5 |
| Discovery year: |
2006-09-21 |
| GenBank acession: |
AA463818 CR747200 DY654432 |
| Entrez gene record: |
387733 |
| Pubmed identfication: |
11106657 12659663 18442316 |
| RefSeq identity: |
NM_001025295 |
| Havana BLAST/BLAT: |
OTTHUMG00000165355 |