| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APOBEC3G |
| Specificity: |
This antibody reacts specifically with APOBEC3G |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human APOBEC3G |
| Gene ID: |
60489 |
| Swiss Prot: |
Q9HC16 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), Exhibits potent antiviral activity against vif-deficient HIV-1, May inhibit the mobility of LTR and non-LTR retrotransposons, Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA, The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, equine infectious anemia virus (EIAV), hepatitis B virus (HBV), it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA, together exert efficient antiretroviral effects in infected target cells, xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV), DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CEM15 MDS019 dJ494G10, 1 FLJ12740 bK150C2, 7 |
| Also known as: |
APOBEC3G Polyclonal Antibody |
| Other name: |
Anti-APOBEC3G Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APOBEC3G |
| Short name: |
Anti-APOBEC3G (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-APOBEC3G (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17357 |
| Gene: |
APOBEC3G |
More about : APOBEC3G |
| Long gene name: |
apolipoprotein B mRNA editing enzyme catalytic subunit 3G |
| Synonyms gene name: |
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| Synonyms name: |
DNA dC->, dU-editing enzyme APOBEC-3G |
| Locus: |
22q13, 1 |
| Discovery year: |
2001-12-12 |
| GenBank acession: |
AF182420 |
| Entrez gene record: |
60489 |
| Pubmed identfication: |
11863358 |
| RefSeq identity: |
NM_021822 |
| Classification: |
Apolipoprotein B mRNA editing enzyme catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000151081 |