| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
C4a+C4b |
| Specificity: |
This antibody reacts specifically with C4a+C4b |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human C4a and C4b Complement C4 beta chain |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
2, Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus, Nov 2011], The alpha chain may be cleaved to release C4 anaphylatoxin, The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, The trimer provides a surface for interaction between the antigen-antibody complex and other complement components, This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6, Two transcript variants encoding different isoforms have been found for this gene, Varying haplotypes of this gene cluster exist, [provided by RefSeq, a mediator of local inflammation, and gamma chains prior to secretion, beta, or 3 copies of this gene, part of the classical activation pathway, such that individuals may have 1, This gene encodes the acidic form of complement factor 4 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Acidic complement C4, Basic complement C4, C4, C4A, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CH, CO4, CO4A_HUMAN, CO4B_HUMAN, CPAMD2, Chido blood group, Complement component 4A, Complement component 4B, RG, RG, Rodgers blood group, complement C4-A proprotein, Complement C4 beta chain |
| Also known as: |
C4a+C4b Polyclonal Antibody |
| Other name: |
Anti-C4a+C4b Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
C4a+C4b |
| Short name: |
Anti-C4a+C4b (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-complement component 4A (Rodgers blood group)+complement component 4B (Chido blood group) (polyclonal) |
| Alternative technique: |
polyclonals |