| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
B7-H3 / CD276 |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB |
| Recommended dilutions: |
ELISA (peptide) LOD: 1:8000, Western blot: 1-3ug/ml |
| Notes: |
Optimal dilution of the B7-H3 antibody should be determined by the researcher |
| Intented use: |
This B7-H3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q5ZPR3 |
| Purity: |
Antigen affinity |
| Description: |
Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy, May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces, May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells, [UniProt], May participate in the regulation of T-cell-mediated immune response |
| Immunogen: |
Amino acids KHSDSKEDDGQE were used as the immunogen for this B7-H3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the B7-H3 antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
B7-H3 / CD276 |
| Short name: |
B7-H3 Antibody / CD276 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
B7-H3 (Antibody to) / CD276 molecule |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD276 and IDBG-21197 and ENSG00000103855 and 80381, CD276 and IDBG-645646 and ENSBTAG00000019734 and 508656, Cd276 and IDBG-172080 and ENSMUSG00000035914 and 102657, Cell surfaces, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0006955 and immune response and biological process this GO :0008283 and cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0045077 and negative regulation of interferon-gamma biosynthetic process and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045085 and negative regulation of interleukin-2 biosynthetic process and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1900042 and positive regulation of interleukin-2 secretion and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, CD276 molecule |
| Identity: |
19137 |
| Gene: |
CD276 |
More about : CD276 |
| Long gene name: |
CD276 molecule |
| Synonyms gene name: |
CD276 antigen |
| Synonyms: |
B7-H3 B7H3 B7RP-2 |
| Locus: |
15q24, 1 |
| Discovery year: |
2005-03-04 |
| GenBank acession: |
AF302102 |
| Entrez gene record: |
80381 |
| Pubmed identfication: |
11224528 12055244 |
| RefSeq identity: |
NM_025240 |
| Classification: |
C2-set domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000137585 |