| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RAP1A |
| Specificity: |
This antibody reacts specifically with RAP1A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RAP1A |
| Gene ID: |
5906 |
| Swiss Prot: |
P62834 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Counteracts the mitogenic function of Ras, Involved in the establishment of basal endothelial barrier function, May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions, Plays a role in nerve growth factor (NGF)-induced neurite outgrowth, Plays a role in the regulation of embryonic blood vessel formation, Together with ITGB1BP1, at least partly because it can interact with Ras GAPs and RAF in a competitive manner, regulates KRIT1 localization to microtubules and membranes, Induces morphological reversion of a cell line transformed by a Ras oncogene |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KREV-1 SMGP21 |
| Also known as: |
RAP1A Polyclonal Antibody |
| Other name: |
Anti-RAP1A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RAP1A |
| Short name: |
Anti-RAP1A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RAP1A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9855 |
| Gene: |
RAP1A |
More about : RAP1A |
| Long gene name: |
RAP1A, member of RAS oncogene family |
| Locus: |
1p13, 2 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
BC014086 |
| Entrez gene record: |
5906 |
| Pubmed identfication: |
3143720 |
| RefSeq identity: |
NM_002884 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000011959 |