| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Purified antibody |
| Conjugation: |
Biotinylated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SOCS1 [Biotin Conjugate] |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), IHC, WB |
| Recommended dilutions: |
ELISA (peptide) LOD: 1:32000, Immunohistochemistry (FFPE): suitable, Western blot: 1-3ug/ml |
| Notes: |
A non-animal protein (NAP) blocker is recommended, Do not use a blocking agent or diluent that contains biotin (including milk and some BSA preparations) when testing with biotinylated antibodies, <, 1, Optimal dilution of the SOCS1 antibody should be determined by the researcher, p> |
| Intented use: |
This SOCS1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
8651 |
| Purity: |
Antigen affinity |
| Description: |
Additional name(s) for this target protein: Suppressor of cytokine signaling 1 |
| Immunogen: |
Amino acids VLRDYLSSFPFQI were used as the immunogen for this SOCS1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the SOCS1 antibody at -20 deg |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SOCS1 [ Conjugate] |
| Short name: |
SOCS1 Antibody [ Conjugate] |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
Biotin |
| Alternative name: |
suppressor on cytokine signaling 1 (Antibody to) [biotinilated Conjugate] |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CIS1 and CISH1 and JAB and SOCS-1 and SSI-1 and SSI1 and TIP3, SOCS1 and IDBG-14621 and ENSG00000185338 and 8651, SOCS1 and IDBG-648701 and ENSBTAG00000004386 and 518795, Socs1 and IDBG-132667 and ENSMUSG00000038037 and 12703, nuclei, protein kinase binding, this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0019210 and kinase inhibitor activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process this GO :0042518 and negative regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0045087 and innate immune response and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0046426 and negative regulation of JAK-STAT cascade and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process, this GO :0004860 : protein kinase inhibitor activity, this GO :0004860 : protein kinase inhibitor activity and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0019210 : kinase inhibitor activity and also this GO :0019901 : protein kinase binding, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005515 : protein binding, this GO :0019210 : kinase inhibitor activity, this GO :0019901 : protein kinase binding, suppressor of cytokine signaling 1 |
| Identity: |
19383 |
| Gene: |
SOCS1 |
More about : SOCS1 |
| Long gene name: |
suppressor of cytokine signaling 1 |
| Synonyms: |
SOCS-1 SSI-1 JAB TIP3 Cish1 |
| Locus: |
16p13, 13 |
| Discovery year: |
2002-11-13 |
| GenBank acession: |
U88326 |
| Pubmed identfication: |
7796808 9266833 |
| Classification: |
Suppressors of cytokine signaling SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129792 |