| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Arfaptin 2 |
| Specificity: |
This antibody reacts specifically with Arfaptin 2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Arfaptin 2 |
| Gene ID: |
23647 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes, The X-ray structure of arfaptin reveals an elongated, but binds to Rac-GTP and Rac-GDP with similar affinities, crescent-shaped dimer of 3-helix coiled-coils, ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
POR1 |
| Also known as: |
Arfaptin 2 Polyclonal Antibody |
| Other name: |
Anti-Arfaptin 2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Arfaptin 2 |
| Short name: |
Anti-Arfaptin 2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Arfaptin 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17160 |
| Gene: |
ARFIP2 |
More about : ARFIP2 |
| Long gene name: |
ADP ribosylation factor interacting protein 2 |
| Synonyms name: |
arfaptin 2 |
| Locus: |
11p15, 4 |
| Discovery year: |
2003-07-21 |
| GenBank acession: |
BC000392 |
| Entrez gene record: |
23647 |
| Pubmed identfication: |
8670882 9038142 |
| RefSeq identity: |
NM_012402 |
| Classification: |
Classical BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133406 |