| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CTNNA3 |
| Specificity: |
This antibody reacts specifically with CTNNA3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CTNNA3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CTNNA3, Catenin/cadherin complexes play an important role in mediating cellular adhesion, alpha T-catenin, alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, also referred to as VR22, and it functions to inhibit Wnt signaling, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy, cytoplasmic proteins that associate with E-cadherin at cellular junctions, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis, is located on chromosome 10, the gene that encodes for alpha-T-catenin, The catenins are ubiquitously expressed |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
VR22 MGC26194 |
| Also known as: |
CTNNA3 Polyclonal Antibody |
| Other name: |
Anti-CTNNA3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CTNNA3 |
| Short name: |
Anti-CTNNA3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, a 3 (polyclonal), antibody to-catenin (cadherin-associated protein) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, CTNNA3 and IDBG-75710 and ENSG00000183230 and 29119, Cell surfaces, Ctnna3 and IDBG-159580 and ENSMUSG00000060843 and 216033, actin filament binding, alpha 3, this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005916 and fascia adherens and cellular component this GO :0007155 and cell adhesion and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030027 and lamellipodium and cellular component this GO :0045296 and cadherin binding and molecular function this GO :0051015 and actin filament binding and molecular function, this GO :0005198 : structural molecule activity, this GO :0005198 : structural molecule activity and also this GO :0005515 : protein binding and also this GO :0045296 : cadherin binding and also this GO :0051015 : actin filament binding, this GO :0005515 : protein binding, this GO :0045296 : cadherin binding, this GO :0051015 : actin filament binding, 102825 and IDBG-629096 and ENSBTAG00000045699 and 780777, catenin (cadherin-associated protein) |
| Identity: |
2511 |
| Gene: |
CTNNA3 |
More about : CTNNA3 |
| Long gene name: |
catenin alpha 3 |
| Synonyms gene name: |
alpha 3 , catenin (cadherin-associated protein) |
| Locus: |
10q21, 3 |
| Discovery year: |
2000-03-29 |
| GenBank acession: |
AF091606 |
| Entrez gene record: |
29119 |
| Pubmed identfication: |
12596047 11590244 |
| RefSeq identity: |
NM_013266 |
| Havana BLAST/BLAT: |
OTTHUMG00000018334 |