| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Protocadherin 10 |
| Specificity: |
This antibody reacts specifically with Protocadherin 10 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PCDH10 |
| Gene ID: |
57575 |
| Swiss Prot: |
Q9P2E7 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expressed at moderate levels in brain, PCDH10 (protocadherin 10), PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor, PCDH10 is associated with the progression of various carcinomas, There are three protocadherin gene clusters, When underexpressed, all of which contain multiple tandemly arranged genes, also known as PCDH19 or OL-PCDH, beta and gamma, designated alpha, including gastric cancer, is a 1, ovary and testis and present at lower levels in all other tissues, 040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Protocadherin 10 Polyclonal Antibody |
| Other name: |
Anti-Protocadherin 10 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Protocadherin 10 |
| Short name: |
Anti-Protocadherin 10 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Protocadherin 10 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8681 |
| Gene: |
PCDHB10 |
More about : PCDHB10 |
| Long gene name: |
protocadherin beta 10 |
| Locus: |
5q31, 3 |
| Discovery year: |
2000-06-28 |
| GenBank acession: |
AF152489 |
| Entrez gene record: |
56126 |
| Pubmed identfication: |
10380929 |
| RefSeq identity: |
NM_018930 |
| Classification: |
Clustered protocadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000129626 |