| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TIFA |
| Specificity: |
This antibody reacts specifically with TIFA |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TIFA |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Induces the oligomerization and polyubiquitination of TRAF6, resulting in the downstream activation of NF-kappa-B and AP-1 pathways, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism, Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC20791 T2BP T6BP TIFAA |
| Also known as: |
TIFA Polyclonal Antibody |
| Other name: |
Anti-TIFA Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TIFA |
| Short name: |
Anti-TIFA (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TIFA (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19075 |
| Gene: |
TIFA |
More about : TIFA |
| Long gene name: |
TRAF interacting protein with forkhead associated domain |
| Synonyms gene name: |
TRAF-interacting protein with forkhead-associated domain |
| Synonyms name: |
TRAF2 binding protein TRAF6 binding protein |
| Locus: |
4q25 |
| Discovery year: |
2008-03-17 |
| GenBank acession: |
BC008294 |
| Entrez gene record: |
92610 |
| Pubmed identfication: |
1179819 |
| RefSeq identity: |
NM_052864 |
| Havana BLAST/BLAT: |
OTTHUMG00000161066 |