| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GPR19 |
| Specificity: |
This antibody reacts specifically with GPR19 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human G protein coupled receptor 19 |
| Gene ID: |
2828 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation), GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions, GPR19, The GPR19 gene maps to a location on chromosome 12, They respond to a great variety of signaling molecules, also known as seven transmembrane receptors, an orphan receptor, are members of the largest protein family and play a role in many different stimulus-response pathways, heptahelical receptors, hypothalamic nuclei and the cerebellum, including hormones, including the olfactory bulb, neurotransmitters and other proteins and peptides, or 7TM receptors, shows elevated expression during embyronic development of the nervous sytem as well as in specific regions of adult mouse brain, the hippocampus, which is a frequent target for rearrangement in cancer cells and involved in childhood acute lymphoblastic leukemia (ALL), G protein-coupled receptors (GPRs or GPCRs) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GPR19 Polyclonal Antibody |
| Other name: |
Anti-GPR19 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GPR19 |
| Short name: |
Anti-GPR19 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GPR19 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4473 |
| Gene: |
GPR19 |
More about : GPR19 |
| Long gene name: |
G protein-coupled receptor 19 |
| Locus: |
12p13, 1 |
| Discovery year: |
1996-08-08 |
| Entrez gene record: |
2842 |
| RefSeq identity: |
NM_006143 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000168705 |